914487
2-(Diphenylphosphanyl)benzamide
≥95%
别名:
2-(Diphenylphosphino)-benzamide, DPBM, Phosphine for Staundinger reduction
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C19H16NOP
化学文摘社编号:
分子量:
305.31
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Assay:
≥95%
Form:
powder
Quality Level
assay
≥95%
form
powder
storage temp.
−20°C
SMILES string
P(c3c(cccc3)C(=O)N)(c2ccccc2)c1ccccc1
InChI
1S/C19H16NOP/c20-19(21)17-13-7-8-14-18(17)22(15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H,(H2,20,21)
InChI key
IHGZKYLRNBICEF-UHFFFAOYSA-N
General description
It is recommended to make fresh stock stolutions prior to each use.
Application
2-(Diphenylphosphanyl)benzamide (DPBM) is a phosphine useful in the Staudinger reduction in chemical biology and medicinal chemistry. Recently, DPBM was demonstrated to faciliate the reactivation of CRISPR/Cas9 functions by removing azidomethylnicotinyl (AMN) groups used to masked gRNA and inhibit CRISPR systems. AMN groups were originally added with the use of RNA probe NAI-N3 (cat# 913812).
存储类别
11 - Combustible Solids
wgk
WGK 3
Ji Luo et al.
Nature chemistry, 8(11), 1027-1034 (2016-10-22)
Using small molecules to control the function of proteins in live cells with complete specificity is highly desirable, but challenging. Here we report a small-molecule switch that can be used to control protein activity. The approach uses a phosphine-mediated Staudinger
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 914487-250MG | 04061842083329 |
| 914487-50MG | 04061842083336 |