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Merck
CN

8.41359

Triisopropylsilane

for synthesis

别名:

Triisopropylsilane

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关于此项目

线性分子式:
((CH3)2CH)3SiH
化学文摘社编号:
分子量:
158.36
UNSPSC Code:
12352103
NACRES:
NA.22
MDL number:
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Quality Level

assay

≥98.0% (GC)

form

liquid

bp

84-85 °C/46.7 hPa

transition temp

flash point 35 °C

density

0.77 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

[SiH](C(C)C)(C(C)C)C(C)C

InChI

1S/C9H22Si/c1-7(2)10(8(3)4)9(5)6/h7-10H,1-6H3

InChI key

YDJXDYKQMRNUSA-UHFFFAOYSA-N

Application

  • Total synthesis of diazaquinomycins H and J using double Knorr cyclization: This paper covers the first total synthesis of diazaquinomycins, highlighting the role of triisopropylsilane in enhancing reaction efficiency (Prior & Sun, 2019).
  • Reduction of cysteine‐S‐protecting groups by triisopropylsilane: An in-depth look at the chemical properties of triisopropylsilane, emphasizing its effectiveness in peptide synthesis processes (Ste. Marie & Hondal, 2018).

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.765 - 0.772
Identity (IR): passes test


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pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

100.4 °F - closed cup

flash_point_c

38 °C - closed cup



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实验方案

Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.





全球贸易项目编号

货号GTIN
841359999904022536779911
841359001004022536635682