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ABE457

抗-c-Fos抗体

Name: 抗-c-Fos抗体
Brand: MM

rabbit polyclonal

别名:

Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

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关于此项目

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Clone:

polyclonal

Species reactivity:

human, rat

Application:

IHC, WB

Citations:

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属性

产品名称

抗-c-Fos抗体, from rabbit, purified by affinity chromatography

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat

species reactivity (predicted by homology)

sheep (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), porcine (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

NCBI accession no.

NP_005243

UniProt accession no.

P01100

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FOS(2353)

说明

General description

c-Fos是也被鉴定为原癌基因的立即早期基因（IEG）转录因子家族的成员（其他成员包括Jun和Egr-1）。c-Fos和其他IEG的基础表达通常较低，但响应通常由外部刺激（例如应激或神经元激活）引起的细胞活性变化而相对快速且通常急剧增加（mRNA为15-30分钟；蛋白为30-60分钟）。因此，这些IEG用于指示比活驱动的细胞活化，包括鉴别由各种生长因子、神经活性药物激活的神经元以及行为或生理状态的相关变化。

观察值〜60/56 kDa。该蛋白具有通过53和68kDa范围内的选择性剪接产生的多种亚型（Jurado, J., et al. (2007).BMC Molecular Biology.8:83-96.)

Immunogen

对应于人c-Fos N末端的KLH偶联的线性肽。

Application

免疫组化分析：代表性批次的1：1,000稀释液在大鼠脑桥和大鼠小脑组织中检测到c-Fos。

免疫荧光分析：代表性批次在大鼠脑桥和大鼠小脑组织中检测到c-Fos。

抗c-Fos抗体是一种用于检测c-Fos的兔多克隆抗体，也称为原癌基因c-Fos，细胞癌基因fos&已在WB &IHC中得到验证。

Biochem/physiol Actions

该抗体识别c-Fos的N末端。

Analysis Note

对照
PMA（TPA）处理的HeLa细胞裂解物

通过蛋白质印迹在PMA（TPA）处理的HeLa细胞裂解物中的进行了评估。

蛋白质印迹分析：0.5 µg/mL该抗体在10 µg PMA（TPA）处理的HeLa细胞裂解物中检测到c-Fos。

Other Notes

浓度：请参考批次特异性浓缩物的分析证书。

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Anorexia nervosa (AN) is accompanied by severe somatic and psychosocial complications. However, the underlying pathogenesis is poorly understood, treatment is challenging and often hampered by high relapse. Therefore, more basic research is needed to better understand the disease. Since hyperactivity

Suckling-induced Fos activation and melanin-concentrating hormone immunoreactivity during late lactation.

R D Alvisi et al.

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Dysfunction of the striatum is frequently associated with sleep disturbances. However, its role in sleep-wake regulation has been paid little attention even though the striatum densely expresses adenosine A2A receptors (A2ARs), which are essential for adenosine-induced sleep. Here we showed

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全球贸易项目编号

货号	GTIN
ABE457	04053252599552