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Merck
CN

Y0000538

Dexamethasone isonicotinate

European Pharmacopoeia (EP) Reference Standard

别名:

Dexamethasone 21-isonicotinate

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关于此项目

经验公式(希尔记法):
C28H32FNO6
化学文摘社编号:
分子量:
497.56
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

dexamethasone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

F[C@@]21[C@H]([C@H]4[C@@]([C@@]([C@@H](C4)C)(O)C(=O)COC(=O)c5ccncc5)(C[C@@H]2O)C)CCC3=CC(=O)C=C[C@@]31C

InChI

1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

InChI key

BQTXJHAJMDGOFI-NJLPOHDGSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone isonicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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分析证书(COA)

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P L Toutain et al.
Journal of veterinary pharmacology and therapeutics, 5(1), 33-43 (1982-03-01)
The pharmacokinetics of Dexamethasone (DXM) was studied in four cows all of which received DXM alcohol and DXM 21 isonicotinate (as a solution) by the intravenous and intramuscular routes. Concentrations of DXM and cortisol were determined using high performance liquid
[Notes on the disaster in Bhopal].
W F Diller
Deutsche medizinische Wochenschrift (1946), 110(45), 1749-1751 (1985-11-08)
Thomas Wittek et al.
Berliner und Munchener tierarztliche Wochenschrift, 118(3-4), 140-149 (2005-04-05)
The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows received



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货号GTIN
Y000053804061837568916