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Merck
CN

F3917

毛喉素

For use in molecular biology applications

别名:

7β-乙酰氧基-1α,6β,9α-二羟基-8,13-环氧-半日花-14-EN-11-酮, 洋紫苏醇, 考福新

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关于此项目

经验公式(希尔记法):
C22H34O7
化学文摘社编号:
分子量:
410.50
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
266-410-9
Beilstein/REAXYS Number:
1692716
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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biological source

Coleus forskohlii

description

for activation of T cells

product line

BioReagent

assay

≥98% (HPLC)

form

powder

mol wt

410.50  g/mol

color

white to off-white

solubility

ethanol: soluble

suitability

suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells

storage temp.

room temp

SMILES string

CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C

InChI

1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

InChI key

OHCQJHSOBUTRHG-KGGHGJDLSA-N

General description

毛喉素是从Coleus forskohlii分离提取的细胞渗透双萜。

Biochem/physiol Actions

具有抗高血压、正性变力作用和腺苷酸环化酶活化特性的细胞通透性二萜类化合物。它的许多生物学作用是由于其对腺苷酸环化酶的激活以及由此而导致的细胞内cAMP浓度增加。毛喉素可影响钙电流并抑制MAP激酶。


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Dermal

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

Learn how to cultivate similar-sized iPSC-derived colon organoids using Millicell® Microwell plates and perform a forskolin-induced swelling assay.

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全球贸易项目编号

货号GTIN
F3917-10MG04061833617342
F3917-25MG04061833617359