biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
RMdO20, monoclonal
form
buffered aqueous solution
species reactivity
mouse, rat, human
concentration
~2 mg/mL
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, microarray: suitable, western blot: 1-2 μg/mL using extracts of rat brain S1 fraction.
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NEFH(4744), NEFM(4741)
mouse ... Nefh(380684), Nefm(18040)
rat ... Nefh(24587), Nefm(24588)
General description
神经丝直径为10 nm,属于中间丝蛋白家族。 神经丝主要在神经元起源的细胞或组织中表达,对于轴突的适当径向生长至关重要。抗神经丝 160/200 单克隆抗体可用于 ELISA 和免疫印迹。它还可以用于微阵列。小鼠抗神经丝 160/200 抗体与小鼠、大鼠和人体内非磷酸化形式的 NF-M 和 NF-H(NF-M/H,约 160 和 200 kDa)发生特异性反应。
Immunogen
纯化的中等大小大鼠神经丝 (NF-M) 亚基。
Application
单克隆抗神经丝160/200抗体可用于免疫细胞化学(1:100稀释)和蛋白质印迹(1:1,000稀释)。它还可用于免疫组织化学。
Physical form
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
常规特殊物品
此项目有
W Yu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(15), 5782-5791 (2000-07-26)
Dendrites are short stout tapering processes that are rich in ribosomes and Golgi elements, whereas axons are long thin processes of uniform diameter that are deficient in these organelles. It has been hypothesized that the unique morphological and compositional features
Yaxian Wang et al.
International journal of molecular sciences, 18(2) (2017-01-31)
Peripheral nerve injury triggers the dysregulation of a large number of genes at multiple sites, including neurons, peripheral nerve stump, and the target organ. Housekeeping genes were frequently used as reference genes to normalize the expression values of target genes.
M K Lee et al.
Current opinion in cell biology, 6(1), 34-40 (1994-02-01)
Neurofilaments make up the major intermediate filament system in mature neurons. Recent studies demonstrate that neurofilaments in vivo are obligate heteropolymers and are required for proper radial growth of axons. Furthermore, forced over-expression of neurofilament subunits in transgenic mice shows
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N2912-100UL | 04061837720963 |
| N2912-200UL | 04061834115526 |