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Merck
CN

T0656

1,3,4,6-四氯-3α,6α-二苯基甘脲

别名:

Iodo-Gen®, NSC 4462

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关于此项目

经验公式(希尔记法):
C16H10Cl4N4O2
化学文摘社编号:
分子量:
432.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
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storage temp.

2-8°C

Quality Level

SMILES string

ClN1C(=O)N(Cl)C2(N(Cl)C(=O)N(Cl)C12c3ccccc3)c4ccccc4

InChI

1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H

InChI key

FJQZXCPWAGYPSD-UHFFFAOYSA-N

Application

用作氧化剂的放射性碘化用碘化试剂

用于氯胺-T 比较研究的试剂

用于氧化咪唑的试剂

Legal Information

Iodo-Gen is a registered trademark of Pierce Biotechnology, Inc.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Mund et al.
Journal of protein chemistry, 16(3), 161-170 (1997-04-01)
Here we report on the use of iodination of the membrane-bound nicotinic acetylcholine receptor (nAChR) from Torpedo californica electric tissue in order to define surface-exposed portions of the receptor molecule. Membrane-bound nAChR was 125I-iodinated using the oxidation agent Iodo-Gen. The
Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.
P J Fraker et al.
Biochemical and biophysical research communications, 80(4), 849-857 (1978-02-28)
Ganesan Vaidyanathan et al.
Nuclear medicine and biology, 29(1), 1-11 (2002-01-12)
Monoclonal antibodies (mAbs) such as the tumor-specific anti-epidermal growth factor receptor variant III (EGFRvIII) that are internalized and degraded after cell binding necessitate the use of radioiodination methods that minimize the loss of radioactivity from the tumor cell after intracellular



全球贸易项目编号

货号GTIN
T0656-250MG04061833286722
T0656-1G04061826695746