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关于此项目
化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
234-318-8
NACRES:
NA.75
MDL number:
eCl@ss:
34058011
biological source
human plasma
Quality Level
product line
BioReagent
assay
≥98% (agarose gel electrophoresis)
form
powder
mol wt
76-81 kDa
concentration
~25 mM
technique(s)
cell culture | mammalian: suitable
impurities
HIV and HBsAg, source material tested negative, ≤0.005% iron
solubility
H2O: 50 mg/mL
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TF(7018)
Application
载脂蛋白转铁蛋白可以补充铁或用于结合培养基中存在的游离铁,还可用于将铁运输到哺乳动物细胞中。
Biochem/physiol Actions
转铁蛋白是一种存在于血清中的主要铁结合和细胞传递分子。 无血清细胞培养系统需要一种铁的传递形式。 转铁蛋白是铁的优选传递形式,因为细胞可通过细胞表面上的转铁蛋白受体以生理学上适当的方式对转铁蛋白结合的铁进行处理。 人载脂蛋白-转铁蛋白是一种高亲和力的转铁蛋白,可用于多种细胞类型。 载脂蛋白-转铁蛋白可以在使用前装载铁或直接添加到含铁介质中。
Other Notes
非血红素铁转运蛋白。
Disclaimer
供研究使用在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
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存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
高风险级别生物产品--人源产品
此项目有
商品
转铁蛋白和其他细胞培养成分如何影响无血清、无蛋白细胞培养系统(用于生物制造包括单克隆抗体在内的异源蛋白)的性能。本页介绍转铁蛋白的体外化学和生物化学。
Understand how transferrin affects serum-free cell culture systems, crucial for biomanufacturing heterologous proteins like monoclonal antibodies.
Giang D Nguyen et al.
PloS one, 9(5), e96858-e96858 (2014-05-08)
H1 linker histone proteins are essential for the structural and functional integrity of chromatin and for the fidelity of additional epigenetic modifications. Deletion of H1c, H1d and H1e in mice leads to embryonic lethality by mid-gestation with a broad spectrum
Giang D Nguyen et al.
PloS one, 8(8), e72698-e72698 (2013-08-24)
Huntington's disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored.
Ayumu Suzuki et al.
Nature communications, 7, 11056-11056 (2016-03-31)
Meiosis is a unique process that allows the generation of reproductive cells. It remains largely unknown how meiosis is initiated in germ cells and why non-germline cells do not undergo meiosis. We previously demonstrated that knockdown of Max expression, a
全球贸易项目编号
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| T1147-100MG | 04061837336591 |
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| T1147-5G | 04061837336638 |
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