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Merck
CN

T6763

乙酰化胰蛋白酶 来源于牛胰腺

Type V-S, ≥8,500 BAEE units/mg protein (biuret)

别名:

Acetyltrypsin

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关于此项目

UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥8,500 BAEE units/mg protein (biuret)
Biological source:
bovine pancreas
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biological source

bovine pancreas

Quality Level

type

Type V-S

form

powder

specific activity

≥8,500 BAEE units/mg protein (biuret)

UniProt accession no.

storage temp.

−20°C

Gene Information

cow ... TRYP8(282603)

General description

The trypsin molecule has two domains: one is related to the enzyme active site and the tryptophan residues; the other is related to the 8-anilinonaphthalene-1-sulfonate binding.

Application

Trypsin has been used in a study to assess the ontogeny of the endocrine pancreas in the fetal/newborn baboon. Trypsin digestion and hydrogen/deuterium exchange support the transition between inward- and outward-facing conformations during the catalytic cycle of the bacterial multidrug ATP-binding cassette transporter.

Biochem/physiol Actions

Lys-acetylated trypsin is less susceptible to autolysis than the native form.

Preparation Note

Prepared by the method of Labouesse, J. and Gervais, M., Eur. J. Biochem., 2, 215 (1967).

Other Notes

One BAEE unit will produce a ΔA253 of 0.001 per min at pH 7.6 at 25° C using BAEE as substrate. Reaction volume = 3.2 mL (1 cm light path).
View more information on trypsin at www.sigma-aldrich.com/enzymeexplorer.


pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

低风险生物材料
常规特殊物品

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历史批次信息供参考:

分析证书(COA)

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Shamus P Keeler et al.
Journal of immunology (Baltimore, Md. : 1950), 201(8), 2354-2368 (2018-09-14)
Clinical and experimental observations suggest that chronic lung disease is linked to respiratory viral infection. However, the long-term aspect of this relationship is not yet defined using a virus that replicates at properly high levels in humans and a corresponding
R F Regan et al.
Journal of neurochemistry, 70(1), 77-85 (1998-01-09)
The effect of magnesium on the oxidative neuronal injury induced by hemoglobin was assessed in murine cortical cell cultures. Exposure to 5 microM hemoglobin in physiologic (1 mM) magnesium for 26 h resulted in the death of about one-half the
Amy R Quinn et al.
The Journal of endocrinology, 214(3), 289-299 (2012-06-23)
Erratic regulation of glucose metabolism including hyperglycemia is a common condition in premature infants and is associated with increased morbidity and mortality. The objective of this study was to examine histological and ultrastructural differences in the endocrine pancreas in fetal



全球贸易项目编号

货号GTIN
T6763-1G04061837371936
T6763-100MG04061837371929
T6763-250MG04061832708102