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Merck
CN

1255001

USP

雌素酮

United States Pharmacopeia (USP) Reference Standard

别名:

雌素酮, 3-羟基雌甾-1,3,5(10)-三烯-17-酮, 雌(三烯酚)酮, 雌酮

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关于此项目

经验公式(希尔记法):
C18H22O2
化学文摘社编号:
分子量:
270.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1915077
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grade

pharmaceutical primary standard

API family

estrone

manufacturer/tradename

USP

mp

258-260 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChI key

DNXHEGUUPJUMQT-CBZIJGRNSA-N

Gene Information

human ... ESR1(2099)

Application

Estrone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Conjugated Estrogens
  • Conjugated Estrogens Tablets
  • Esterified Estrogens
  • Esterified Estrogens Tablets
  • Estradiol
  • Estradiol and Norethindrone Acetate Tablets
  • Estradiol Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Robert E Nelson et al.
Clinical chemistry, 50(2), 373-384 (2003-12-06)
Estradiol (E2) and estrone (E1) measurements form an integral part of the assessment of female reproductive function and have expanding roles in other fields. However, many E1 and E2 immunoassays have limited functional sensitivity, suffer from cross-reactivity, and display poor
Fluorometric determination of plasma 11-hydroxycorticosteroids. II. Studies on the specificity of the method.
L E Mejer et al.
Clinical chemistry, 19(7), 718-724 (1973-07-01)
Shanshan Zhao et al.
Breast cancer research : BCR, 16(2), R30-R30 (2014-03-29)
Paradoxically, a breast cancer risk reduction with conjugated equine estrogens (CEE) and a risk elevation with CEE plus medroxyprogesterone acetate (CEE + MPA) were observed in the Women's Health Initiative (WHI) randomized controlled trials. The effects of hormone therapy on serum sex



全球贸易项目编号

货号GTIN
1255001-200MG04061838723604