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MMP3

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Synonyms:
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1
Species:
UniProtKB ID:
Gene ID:
  • Human(4314) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17392) matrix metallopeptidase 3
  • Rat(171045) matrix metallopeptidase 3
  • cow(281309) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • Horse(100034195) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic cat(493666) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • dog(403445) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic cat(101081492) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • sheep(101118895) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic guinea pig(100729101) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • Domestic Rabbit(100009111) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • naked mole-rat(101716622) matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Mouse MMP-3 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Human MMP-3 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-MMP3 antibody produced in mouse, clone 4C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
Anti-MMP-3 Antibody, NT, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, human, rhesus macaque, rhesus monkey
Application
immunohistochemistry
western blot
Anti-MMP-3 (Ab-1) Mouse mAb (55-2A4), liquid, clone 55-2A4, Calbiochem®,
Species Reactivity
human, porcine, rat, sheep
Application
Anti-MMP-3 Antibody, clone SL-1 IID4, clone SL-1 IID4, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
4-Phenylpyridine, 97%,
Species
human
Acetohydroxamic acid, 98%,
Species
human
4,4′-Dihydroxybiphenyl, 97%,
Species
human
4′-Hydroxy-4-biphenylcarbonitrile, 97%,
Species
human
α-Sexithiophene, ,
Species
human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP3,
Species
human
MISSION® esiRNA, targeting mouse Mmp3,
Species
mouse