914134
5-(Biotinamido)pentylamine TFA Salt
≥95%
Synonym(s):
N-(5-Aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pent, Biotin cadaverine TFA, Biotin-DAPe TFA
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About This Item
Empirical Formula (Hill Notation):
C15H28N4O2S · xC2HF3O2
Molecular Weight:
328.47 (free base basis)
UNSPSC Code:
12352116
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder
Quality Level
assay
≥95%
form
powder
mp
116-121 °C
storage temp.
2-8°C
SMILES string
FC(F)(F)C(=O)O.S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCCCCN
InChI key
QWKKJNXOPDNIEU-RGESYUBESA-N
Application
5-(Biotinamido)pentylamine TFA Salt is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.
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Other Notes
Site-selective conversion of azido groups at carbonyl α-positions into oxime groups leading triazide to a triple click conjugation scaffold
Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions
Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation
Synthesis of Novel Phosphonic-Type Activity-Based Probes for Neutrophil Serine Proteases and Their Application in Spleen Lysates of Different Organisms
Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions
Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation
Synthesis of Novel Phosphonic-Type Activity-Based Probes for Neutrophil Serine Proteases and Their Application in Spleen Lysates of Different Organisms
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Marianne van Wyk et al.
Chemical communications (Cambridge, England), (4), 398-400 (2007-01-16)
Coenzyme A analogues are synthesized in a one-pot preparation by biotransformation of pantothenate thioesters through the simultaneous use of three CoA biosynthetic enzymes, followed by aminolysis.
Sung Kook Chun et al.
ACS chemical biology, 9(3), 703-710 (2014-01-07)
Circadian rhythms, biological oscillations with a period of about 24 h, are maintained by a genetically determined innate time-keeping system called the molecular circadian clockwork. Despite the physiological and clinical importance of the circadian clock, the development of small molecule
Taiki Yokoi et al.
Chemical communications (Cambridge, England), 55(13), 1891-1894 (2018-12-21)
This paper reports the selective conversion of alkyl azido groups at the carbonyl α-position into oximes through β-elimination of dinitrogen, followed by transoximation. With this method and diazo conversion, a triazido molecule was transformed into a triple click conjugation scaffold
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 914134-250MG | 04061842072347 |