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Merck
CN

914460

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride

≥95%

Synonym(s):

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride, N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide hydrochloride, N-{2-[2-(2- Aminoethoxy)ethoxy]ethoxy}biotinamide hydrochloride, Amine-terminated biotin linker, Biotin-DOOA HCl, Biotinylation reagent

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About This Item

Empirical Formula (Hill Notation):
C16H31ClN4O4S
CAS Number:
Molecular Weight:
410.96
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.22
Assay:
≥95%
Form:
powder
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Quality Level

assay

≥95%

form

powder

storage temp.

2-8°C

SMILES string

S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCOCCOCCN.Cl

InChI

1S/C16H30N4O4S.ClH/c17-5-7-23-9-10-24-8-6-18-14(21)4-2-1-3-13-15-12(11-25-13)19-16(22)20-15;/h12-13,15H,1-11,17H2,(H,18,21)(H2,19,20,22);1H/t12-,13-,15-;/m0./s1

InChI key

UNQYTGLJZONNBD-HZPCBCDKSA-N

Application

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Zhiyuan Fang et al.
Chemical communications (Cambridge, England), 49(55), 6164-6166 (2013-06-04)
A direct ELISA was established for the fast detection of semicarbazide (SEM) using a novel biotin derivative. Without a tedious extraction procedure, as low as 0.07 μg L(-1) of SEM could be detected reproducibly. This assay has better recovery and
Yali Yuan et al.
Chemical communications (Cambridge, England), 54(80), 11352-11355 (2018-09-25)
We have developed highly fluorescent, monolithic colloidal CdSe seeded CdS nanorod clusters comprising thousands of nanorods. Their use in the sandwich assay detection of a model protein yields a thousand-fold improvement in the detection limit compared to individual nanorods, making
Benjamin Spangler et al.
ACS chemical biology, 14(4), 725-734 (2019-03-26)
Compartmentalization is a crucial facet of many biological systems, and key aspects of cellular processes rely on spatial segregation within the cell. While many drug targets reside in specific intracellular compartments, the tools available for assessing compound exposure are generally



Global Trade Item Number

SKUGTIN
914460-50MG04061842093526