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Merck
CN

914983

ThT-NE

≥95%

Synonym(s):

2-(4-(Diethylamino)phenyl)-3,6-dimethylbenzo[d]thiazol-3-ium chloride, Fluorogenic viral RNA probe, G-Quadruplex Probe, Viral RNA light-up probe

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About This Item

Empirical Formula (Hill Notation):
C19H23ClN2S
CAS Number:
Molecular Weight:
346.92
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
Storage temp.:
−20°C
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Quality Level

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[s]1c2c([n+](c1c3ccc(cc3)N(CC)CC)C)ccc(c2)C

InChI key

WPIXUKQQLRQGGY-UHFFFAOYSA-N

Application

ThT-NE is a benzothiazole-based G-quadruplex (G4)-targeted fluorogenic probe developed by Zhou Nie and coworkers for the visualization of viral RNA in living host cells, including staining, real-time, and live-cell tracking applications.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Xingyu Luo et al.
Journal of the American Chemical Society, 141(13), 5182-5191 (2019-03-13)
RNA viruses represent a major global health threat, and the visualization of their RNA genome in infected cells is essential for virological research and clinical diagnosis. Due to the lack of chemical toolkits for the live-cell imaging of viral RNA



Global Trade Item Number

SKUGTIN
914983-10MG04061842083978