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925047

KB02-COOH

Name: KB02-COOH
Brand: ALDRICH

Synonym(s):

2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid, Functionalized scout fragment

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₄ClNO₄

CAS Number:

2375196-30-6

Molecular Weight:

283.71

MDL number:

MFCD00003568

NACRES:

NA.22

UNSPSC Code:

12352200

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Properties

reaction suitability

reagent type: chemical modification reagent

Quality Level

100

storage temp.

2-8°C

Description

Application

KB02-COOH is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131).

Related useful products may include cysteine fragment KB02 (912131), KB02-SLF (914738), IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059).

Technology spotlight: Proteomic Ligandability Assessment

Other Notes

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKU	GTIN
925047-10MG	04065267409795