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Merck
CN

QACIDSET

QuicTPD Acid Optimization Set

greener alternative
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About This Item

NACRES:
NA.21
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Quality Level

sustainability

Greener Alternative Product

greener alternative category

storage temp.

2-8°C

General description

This set includes 4 representative partial PROTACs, each provided at 5 micromole quantity.
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.

Application

The QuicTPD Acid Optimization set is designed to facilitate high throughput synthesis optimization for researchers working with PROTACs.

Features and Benefits

Two of these PROTACs are tailored to target the CRBN E3 ligase, while the other two are directed towards VHL, incorporating both hydrophobic and hydrophilic linkers. By utilizing this optimization set, customers can explore a variety of reaction conditions—up to 24 or more—before proceeding to the complete screening set. This exploration includes testing different coupling reagents, solvents, and bases, allowing for a comprehensive assessment of the synthesis parameters that influence the efficiency and yield of the desired products.

Other Notes

QuicTPD Acid Screening Set

Legal Information

QuicTPD is a trademark of Merck KGaA, Darmstadt, Germany


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • Pomalidomide-PEG2-CO2H, 95%
    SDS

  • Pomalidomide-C6-CO2H, ≥98%
    SDS

  • VH 032 amide-PEG2-acid, ≥95%
    SDS

  • VH 032 amide-alkyl C5-acid, ≥95%
    SDS

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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Global Trade Item Number

SKUGTIN
QACIDSET-1KT04065272379762