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About This Item
Empirical Formula (Hill Notation):
C37H72O8PNa
CAS Number:
Molecular Weight:
698.93
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
17:0 PA, 1,2-diheptadecanoyl-sn-glycero-3-phosphate (sodium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (830856P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 830856P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCC)O
InChI
1S/C37H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(38)43-33-35(34-44-46(40,41)42)45-37(39)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35H,3-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/t35-;/m1./s1
InChI key
IAELRFKIVVBNTO-RUQJKXHKSA-M
General description
Phosphatidic acid (PA), a phospholipid is a minor component of the phospholipid pool. It is made up of two fatty acids and a phosphate group and are covalently attached with the help of ester linkage to a glycerol molecule. PA is an important constituent of cell membranes.
Application
17:0 PA has been used as an internal standard for BXD liver samples/lipidomics analysis and as an internal standard for BXD plasma sample analysis. It may be used as a component in internal standard mix to spike the brain tissue homogenate.
Biochem/physiol Actions
Phosphatidic acid (PA) serves as a lipid messenger. It can enhance the production of muscle protein. PA can also serve as a signaling lipid. It plays a key role in mammalian target of rapamycin (mTOR) signaling.
Packaging
5 mL Amber Glass Screw Cap Vial (830856P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Jadegoud Yaligar et al.
PloS one, 9(3), e91436-e91436 (2014-03-19)
Dietary saturated fatty acids contribute to the development of fatty liver and have pathogenic link to systemic inflammation. We investigated the effects of dietary fat towards the pathogenesis of non-alcoholic fatty liver disease by longitudinal in vivo magnetic resonance spectroscopy
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 830856P-25MG | 04061835228454 |