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Merck
CN

1.09684

Formamide

for analysis EMSURE®

Synonym(s):

Formic acid amide, Methane amide, Amide C1, Formic amide

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About This Item

Linear Formula:
HCONH2
CAS Number:
Molecular Weight:
45.04
UNSPSC Code:
12191502
NACRES:
NB.21
EC Index Number:
200-842-0
MDL number:
Beilstein/REAXYS Number:
505995
Assay:
≥99.2% (N)
Grade:
reagent grade
Bp:
210 °C (lit.)
Vapor pressure:
0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)
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grade

reagent grade

Quality Level

vapor density

1.55 (vs air)

vapor pressure

0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)

product line

EMSURE®

assay

≥99.2% (N)

form

liquid

autoignition temp.

932 °F

potency

5325 mg/kg LD50, oral (Rat), 17000 mg/kg LD50, skin (Rabbit)

expl. lim.

2.7-19.0 % (v/v)

dilution

(for analytical testing)

impurities

≤0.005% Sulfated ash (600 °C), ≤0.02% Formic acid, ≤0.1% Ammonium Formate, ≤0.1% Water (Karl Fischer), ≤1 ppm Cd (Cadmium), ≤1 ppm Chloride (Cl), ≤1 ppm Cu (Copper)

color

clear, APHA: ≤10

refractive index

n20/D 1.447 (lit.)

pH

8-10 (20 °C, 200 g/L in H2O)

bp

210 °C (lit.)

mp

2-3 °C (lit.)

transition temp

flash point 175 °C

density

1.134 g/mL at 25 °C (lit.)

cation traces

Fe: ≤1  ppm, Pb: ≤1  ppm, Zn: ≤1  ppm

storage temp.

15-25°C

SMILES string

NC=O

InChI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChI key

ZHNUHDYFZUAESO-UHFFFAOYSA-N

General description

EMSURE grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE provides worldwide best and most extensive product specifications. We declare our EMSURE range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.

Application

Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures.

Other Notes

Discover EMSURE - to be more than sure!
Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B - STOT RE 2 Oral

target_organs

Blood

wgk

WGK 1

flash_point_f

305.6 °F

flash_point_c

152 °C

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



Certificates of Analysis (COA)

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Protocols

With the exception of prolin, amino acids are hardly soluble in alcohols. Therefore, only the adherent moisture can be determined by the direct volumetric method.

Summary application report for analysis of moisture in Confectionery

Foodstuffs often provide a challenge for the water determination by Karl-Fischer. Instant Coffee is such a sample matrix and its water content has influence on quality and shelf life.

View All Protocols

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Global Trade Item Number

SKUGTIN
109684100004022536117294
109684250004022536117317