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Merck
CN

1.00577

Water

suitable for GC-HS, SupraSolv®, according to USP and Ph. Eur.

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About This Item

Linear Formula:
H2O
CAS Number:
Molecular Weight:
18.02
UNSPSC Code:
41104213
NACRES:
NA.03
MDL number:
Beilstein/REAXYS Number:
2050024
Technique(s):
GC-HS: suitable
Bp:
100 °C (lit.)
Vapor pressure:
23 hPa ( 20 °C)
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Product Name

Water, for headspace gas chromatography SupraSolv®

Quality Level

agency

according to Ph. Eur., according to USP

vapor pressure

23 hPa ( 20 °C)

product line

SupraSolv®

form

liquid

technique(s)

GC-HS: suitable

impurities

≤1 μg/g Every residual solvent of class 1 acc. to ICH, ≤10 μg/g Every residual solvent of class 2 acc. to ICH, ≤50 μg/g Every residual solvent of class 3 acc. to ICH

evapn. residue

≤5 mg/L

pH

7 (20 °C)

bp

100 °C (lit.)

mp

0 °C (lit.)

storage temp.

2-30°C

SMILES string

O

InChI

1S/H2O/h1H2

InChI key

XLYOFNOQVPJJNP-UHFFFAOYSA-N

General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all residual solvents defined by the ICH.

Application


  • Novel Insights into Sb(III) Oxidation and Immobilization during Ferrous Iron Oxygenation: The Overlooked Roles of Singlet Oxygen and Fe (oxyhydr)oxides Formation.: Discusses the impact of water chemistry on the oxidation processes of antimony and iron, contributing to environmental chemistry and pollution control (Wang et al., 2024).

  • Exposure And Health Risk Assessment Of Aflatoxins In Hot Red Pepper Marketed In North Shewa Zone, Oromia Region, Ethiopia.: Assesses the role of water in transporting and dissolving aflatoxins, with implications for food safety and analytical methodologies in developing countries (Alemu Degefe et al., 2024).


Analysis Note

residue on evaporation: ≤ 5 mg/l
GC/HS
Every residual solvent of class 1 acc. to ICH: ≤ 1 µg/g
Every residual solvent of class 2 acc. to ICH: ≤ 10 µg/g
Every residual solvent of class 3 acc. to ICH: ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, N,N-dimethylacetamide, N,N-dimethy lformamide and dimethyl sulfoxide are not detected.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
100577100004027269298784
100577250004027269298791