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Merck
CN

437557

Acetonitrile

≥99.5%, ACS reagent, suitable for solid phase extraction (SPE)

Synonym(s):

Methyl cyanide, Anhydrous ACN, Dry MeCN

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About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
UNSPSC Code:
12352001
PubChem Substance ID:
EC Number:
200-835-2
Beilstein/REAXYS Number:
741857
MDL number:
Assay:
≥99.5%
Grade:
ACS reagent
Technique(s):
solid phase extraction (SPE): suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)
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Product Name

Acetonitrile, ≥99.5%, ACS reagent

grade

ACS reagent

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

technique(s)

solid phase extraction (SPE): suitable

impurities

≤0.3% water, ≤0.6 μeq/g Titr. base, ≤8 μeq/g Titr. acid

evapn. residue

≤0.005%

color

APHA: ≤10

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

solubility

water: soluble

density

0.786 g/mL at 25 °C (lit.)

format

neat

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

General description

Acetonitrile (MeCN), an aliphatic nitrile, is a colorless liquid with a characteristic odor. MeCN has low viscosity, high elution strength and is highly miscible in water. It is widely used as a solvent and intermediate in organic syntheses and is transparent to UV-visible light, making it highly applicable in spectrophotometric and fluorimetric techniques. It also plays a major role as an extractant medium in liquid-liquid extraction, solid-phase extraction or microextraction.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application

Acetonitrile may be used as solvent in the following processes:
  • Organic synthesis
  • Liquid-liquid extraction, solid-phase extraction or microextraction.
  • Spectrophotometric and fluorimetric techniques.
  • Electrolytes in lithium-ion batteries
  • Determination of pKa values of organic superbases using the isodensity polarization continuum model (IPCM).

Features and Benefits

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.


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pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Basicity of some organic superbases in acetonitrile.
Kovacevic B and Maksic ZB.
Organic Letters, 3(10), 1523-1526 (2001)
Dynamics of ultrafast intramolecular charge transfer with 4-(dimethylamino) benzonitrile in acetonitrile.
Druzhinin SI, et al.
The Journal of Physical Chemistry A, 110(9), 2955-2969 (2006)
Cerium (III) chloride promoted highly regioselective ring opening of epoxides and aziridines using NaN3 in acetonitrile: a facile synthesis of 1,2-azidoalcohols and 1,2-azidoamines.
Sabitha G, et al.
Organic Letters, 4(3), 343-345 (2002)



Global Trade Item Number

SKUGTIN
437557-4L04061837566561
437557-4X4L04061837566578