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Merck
CN

932213

XantPhos Pd G3 ChemBeads

greener alternative

solid

Synonym(s):

[(4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C52H45NO4P2PdS
CAS Number:
Molecular Weight:
948.35
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
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Product Name

XantPhos Pd G3 ChemBeads,

Quality Level

product line

ChemBeads

form

solid

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

InChI key

OIQIZOZMASPGRN-UHFFFAOYSA-M

General description

XantPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XantPhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Greener Chemistry. ChemBeads are advanced solid-coated beads for high-throughput experimentation in various chemical applications. They enable precise dispensing of solid reagents, allowing researchers to conduct reactions with minimal material use, thus supporting waste prevention and catalysis principles while ensuring accuracy and reproducibility. This technology enhances efficiency and streamlines experimental processes in chemistry. Click here for more information.

Application

XantPhos Pd G3 may be used in the following processes:

Negishi cross-coupling reaction during the synthesis of palmerolides.
Aminocarbonylation of heteroaryl bromides with carbon monoxide (CO) in the presence of triethylamine.
Coupling between polyglycosyl thiols and aglycon halides by C-S bond formation.

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Learn more about ChemBeads products

Product is also available as neat precatalyst (763039)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Articles

ChemBeads, catalyst-coated glass beads, dispense solid chemical reagents for nanomole-scale high-throughput reaction screening.





Global Trade Item Number

SKUGTIN
932213-1G04065269195412