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About This Item
Linear Formula:
CH3CONHC6H4OH
CAS Number:
Molecular Weight:
151.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-157-5
Beilstein/REAXYS Number:
2208089
MDL number:
grade
pharmaceutical primary standard
description
API family: acetaminophen
API family
paracetamol, acetaminophen
manufacturer/tradename
EDQM
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
168-172 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
CC(=O)Nc1ccc(O)cc1
InChI
1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
InChI key
RZVAJINKPMORJF-UHFFFAOYSA-N
Gene Information
human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Analgesic.
Paracetamol EP reference standard, intended for use only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
364.3 °F - Pensky-Martens closed cup
flash_point_c
184.6 °C - Pensky-Martens closed cup
Regulatory Information
涉药品监管产品
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S M de Morais et al.
Gastroenterology, 102(2), 577-586 (1992-02-01)
Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
Karel Allegaert et al.
Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
Edward Munsterhjelm et al.
Anesthesiology, 103(4), 712-717 (2005-09-30)
Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P0300000 | 04061834290988 |