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PHR1745

4-Aminophenol hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-Aminophenol hydrochloride, 4-Hydroxyaniline hydrochloride

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About This Item

Linear Formula:
H2NC6H4OH · HCl
CAS Number:
51-78-5
Molecular Weight:
145.59
UNSPSC Code:
12352107
NACRES:
NA.24
PubChem Substance ID:
329823590
EC Number:
200-122-6
Beilstein/REAXYS Number:
3911747
MDL number:
MFCD00012996
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1021204

API family

mesalazine, phenacetin, paracetamol

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

300-305 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cl[H].Nc1ccc(O)cc1

InChI

1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H

InChI key

RVGOBWDGAVAVPJ-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 4-Aminophenol hydrochloride can be used to study cell biology, bioactive small molecules, chemical synthesis, organic building blocks, oxygen compounds and phenols.

Application

4-Aminophenol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using surface enhanced Raman scattering method.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3478 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: From development to method validation
Bleye
Talanta, 116, 899-905 (2013)

Global Trade Item Number

SKUGTIN
PHR1745-500MG04061834802228