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PHR1150

Acetaminophen Related Compound F

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-Nitrophenol, Paracetamol Impurity F, p-Nitrophenol

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About This Item

Linear Formula:
O2NC6H4OH
CAS Number:
100-02-7
Molecular Weight:
139.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823168
EC Number:
202-811-7
Beilstein/REAXYS Number:
1281877
MDL number:
MFCD00007331
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1003064

vapor pressure

0.6 mmHg ( 120 °C)

API family

acetaminophen, paracetamol

CofA

current certificate can be downloaded

autoignition temp.

541 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

279 °C (lit.)

mp

110-115 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O=N(C1=CC=C(O)C=C1)=O

InChI

1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H

InChI key

BTJIUGUIPKRLHP-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8987 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 - STOT RE 2 Oral

target_organs

Kidney,Liver

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

336.2 °F

flash_point_c

169 °C

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

GC Analysis of Phenols in Water

Analytical standard separation of various phenols for research and industrial applications.

Simon De Corte et al.
Colloids and surfaces. B, Biointerfaces, 102, 898-904 (2012-10-31)
An increasing demand for catalytic Pd nanoparticles has motivated the search for sustainable production methods. An innovative approach uses bacterial cells as support material for synthesizing Pd nanoparticles by reduction of Pd(II) with e.g. hydrogen or formate. Nevertheless, drawbacks of
Jau-Rung Chiou et al.
Journal of hazardous materials, 248-249, 394-400 (2013-02-19)
Silver/iron oxide composite nanoparticles have been synthesized successfully via a facile one-pot green route by the use of l-arginine, which created an aqueous solution of about pH 10 and acted as a reducing agent for the successive formation of iron
Siew Hong Lam et al.
Biochimica et biophysica acta, 1830(10), 4778-4789 (2013-06-25)
4-Nitrophenol (4-NP) is a prioritized environmental pollutant and its toxicity has been investigated using zebrafish, advocated as an alternative toxicological model. However, molecular information of 4-NP induced hepatotoxicity is still limited. This study aimed to obtain molecular insights into 4-NP-induced
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Global Trade Item Number

SKUGTIN
PHR1150-1G04061834413547