G4921
Anti-Granulocyte Colony Stimulating Factor antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-G-CSF
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
Neutral, WB
Citations:
5
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
neutralization: suitable, western blot: 0.1-0.2 μg/mL
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Csf3(12985)
Immunogen
purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.
Biochem/physiol Actions
Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Related Content
R R Ji et al.
Nature neuroscience, 2(12), 1114-1119 (1999-11-26)
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Sebastian Stösser et al.
Journal of molecular medicine (Berlin, Germany), 89(4), 321-329 (2010-11-17)
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Sophie Pezet et al.
The European journal of neuroscience, 21(7), 1785-1797 (2005-05-05)
The serine/threonine kinase Akt/PKB has been implicated in cell survival signalling in many cell types, including the dorsal root ganglion (DRG). However, little is known about its role in physiological and pathophysiological conditions in the adult sensory and nociceptive system.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G4921-100UG | 04061831467994 |