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766305

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite

Name: Bis(2-cyanoethyl)-<I>N</I>,<I>N</I>-diisopropylphosphoramidite
Brand: ALDRICH

95%

别名:

Bis(2-cyanoethoxy)(diisopropylamino)phosphine, Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine

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关于此项目

经验公式（希尔记法）:

C₁₂H₂₂N₃O₂P

化学文摘社编号:

102690-88-0

分子量:

271.30

NACRES:

NA.22

PubChem Substance ID:

329767224

UNSPSC Code:

12352200

MDL number:

MFCD00797597

Assay:

95%

Form:

liquid

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属性

Quality Level

100

assay

95%

form

liquid

refractive index

n20/D 1.465

density

1.039 g/mL at 25 °C

storage temp.

−20°C

SMILES string

CC(C)N(C(C)C)P(OCCC#N)OCCC#N

InChI

1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3

InChI key

LDHWBEHZLFDXCU-UHFFFAOYSA-N

说明

General description

Useful phosphorylating reagent used in oligonucleotide synthesis for adding a terminal phosphate group to the 3′ or 5′ hydroxyl.

Application

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite may be used as a phosphitylating agent during the multi-step synthesis of (-)-1L-chiro-inositol 2,3,5-trisphosphate starting from L-quebrachitol.

pictograms

GHS06

signalword

Danger

hcodes

H301 + H311 + H331,H315,H319

pcodes

P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

165.0 °F

flash_point_c

73.9 °C

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis from quebrachitol of 1L-chiro-inositol 2, 3, 5-trisphosphate, an inhibitor of the enzymes of 1D-myo-inositol 1, 4, 5-trisphosphate metabolism.

Liu C, et al.

Carbohydrate Research, 234, 107-115 (1992)

Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.

Francois JC, et al.

Proceedings of the National Academy of Sciences of the USA, 86(24), 9702-9706 (1989)

Solid-phase synthesis of a New Diphosphate 5-Aminoimidazole-4-carboxamide Riboside (AICAR) derivative and studies toward cyclic AICAR diphosphate ribose.

D?Errico S, et al.

Molecules (Basel), 16(9), 8110-8118 (2011)

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全球贸易项目编号

货号	GTIN
766305-1G	04061826736227
766305-5G	04061833340448