914223
Biotin-SLF
别名:
(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4,18-dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosanamido)phenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate, Bio-SLF, Biotin-conjugated FKBP12WT-directed ligand, Biotin-conjugated SLF ligand, FKBP12WT affinity probe for PROTAC® and targeted protein degradation research
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C52H76N6O13S
化学文摘社编号:
分子量:
1025.26
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
ligand
biotin
Quality Level
form
powder
storage temp.
−20°C
SMILES string
O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3
InChI key
QFIMAWUXIBINCP-SLBVAARVSA-N
Application
Biotin-SLF (bio-SLF) is an FKBP12WT affinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation.
Related tools:
Additional bifunctional tools for FKPB12 variants:
Related tools:
Additional bifunctional tools for FKPB12 variants:
- dTAG-13 (SML2601) for FKBP12F36V; and KB02-SLF (914738), KB03-SLF (914975), and KB04-SLF (913715) for FKBP12WT
- Cereblon (CRBN) affinity probe: Biotin-Thalidomide (913979)
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 914223-5MG | 04061842093274 |