产品名称
鞘氨醇（d17:1）, Avanti Research™ - A Croda Brand 860640P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860640P-10mg), pkg of 1 × 5 mg (860640P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860640P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCC
InChI
1S/C17H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h13-14,16-17,19-20H,2-12,15,18H2,1H3/b14-13+/t16-,17+/m0/s1
InChI key
RBEJCQPPFCKTRZ-LHMZYYNSSA-N
General description
鞘氨醇（d17:1）或D-赤型鞘氨醇是一种17碳鞘脂，存在于人体皮肤中。它比天然存在的C18-鞘氨醇少一个碳。
Application
鞘氨醇（d17:1）已被用作脂质标准品，用于通过液相色谱-质谱（LC-MS）和串联质谱法分析鞘脂。
Biochem/physiol Actions
鞘氨醇充当鞘氨醇-1-磷酸（S1P）的前体。鞘氨醇C-17用作通过光谱法分析鞘脂的内标物。
Packaging
5 mL棕色玻璃螺旋盖小瓶（860640P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860640P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
wgk
WGK 3
A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Paugh SW, et al.
Blood, 112(4), 1382-1391 (2008)
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Schull S, et al.
Cell Death & Disease, 6(3), e1691-e1691 (2015)
Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines
Stewart ME and Downing DT
The Journal of Investigative Dermatology, 105(4), 613-618 (1995)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860640P-10MG | 04061835318834 |
| 860640P-5MG | 04061835318841 |