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关于此项目
经验公式(希尔记法):
C33H39BrNO13P
化学文摘社编号:
分子量:
768.54
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
41116105
MDL number:
Assay:
≥97.5% (HPLC), 98%
Quality Level
assay
≥97.5% (HPLC), 98%
technique(s)
MALDI-MS: suitable
storage temp.
−20°C
SMILES string
[Br-].COc1cc(OC)c(c(OC)c1)[P+](CC(=O)ON2C(=O)CCC2=O)(c3c(OC)cc(OC)cc3OC)c4c(OC)cc(OC)cc4OC
InChI
1S/C33H39NO13P.BrH/c1-38-19-12-22(41-4)31(23(13-19)42-5)48(18-30(37)47-34-28(35)10-11-29(34)36,32-24(43-6)14-20(39-2)15-25(32)44-7)33-26(45-8)16-21(40-3)17-27(33)46-9;/h12-17H,10-11,18H2,1-9H3;1H/q+1;/p-1
InChI key
YKMSQZIYVKTUHI-UHFFFAOYSA-M
General description
N-琥珀酰亚胺基-三(2,4,6-三甲氧苯基)磷基溴乙酸酯(TMPP-Ac-OSu)是一种酰化试剂,通常用于肽的N端α-氨基的选择性衍生化。即使不使用自动计算方法,TMPP乙酰化的肽也会发生断裂,从而产生a型离子,使获得序列信息变得更加容易。 在N端肽段的液相色谱偶联质谱(LC-MS/MS)分析中,它可以用作标记试剂,提高电离效率、简化片段化和保留时间,从而更好地分离肽段。
Application
在串联质谱法中,TMPP-Ac-OSu被用于标记肽,以便将精氨酸转化为鸟氨酸,从而改善肽的片段化模式。
Packaging
无底玻璃瓶。内容物在插入式融锥内。
Other Notes
肽 N-末端改性试剂,用于快原子轰击 (FAB) 或基质辅助激光解吸/电离质谱 (MALDI MS)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Z H Huang et al.
Analytical biochemistry, 268(2), 305-317 (1999-03-17)
We have recently reported a simple procedure by which low picomole quantities of peptides can be modified to the corresponding N-Tris(2, 4,6-trimethoxyphenyl)phosphonium-acetyl (TMPP-Ac) derivatives (Z. H Huang, J. Wu, D. A. Gage, and J. T. Watson, Anal. Chem. 69, 137-144
Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol.
Gallien S
Genome Research, 19 (1), 128-135 (2009)
Conversion of arginine to ornithine for improving the fragmentation pattern of peptides labeled with the N-terminal tris (2, 4, 6-trimethoxyphenyl) phosphonium group in tandem mass spectrometry.
Kuyama H
Analytical Methods : Advancing Methods and Applications, 2 (11), 1792-1797 (2010)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 29208-50MG | 04061826594391 |