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Merck
CN

39468

α-氰基-4-羟基肉桂酸

suitable for matrix substance for MALDI-MS, Ultra pure

别名:

α-CCA, α-CHCA, α-氰基, 4-HCCA, ACCA

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关于此项目

线性分子式:
HOC6H4CH=C(CN)CO2H
化学文摘社编号:
分子量:
189.17
UNSPSC Code:
41116105
NACRES:
NA.21
PubChem Substance ID:
EC Number:
248-879-1
Beilstein/REAXYS Number:
3271427
MDL number:
Form:
solid
Quality level:
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Quality Level

form

solid

analyte chemical class(es)

glycans, peptides, proteins

technique(s)

MALDI-MS: suitable

mp

245-250 °C

solubility

methanol: 10 mg/mL, clear

cation traces

Al: ≤1 mg/kg, Ba: ≤1 mg/kg, Ca: ≤1 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤1 mg/kg, Li: ≤1 mg/kg, Mg: ≤1 mg/kg, Mn: ≤1 mg/kg, Na: ≤1 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg

suitability

suitable for matrix substance for MALDI-MS

storage temp.

2-8°C

SMILES string

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI key

AFVLVVWMAFSXCK-VMPITWQZSA-N

General description

α-氰基-4-羟基肉桂酸(α-CHCA)起基质的作用,有助于在基质辅助激光解吸/电离(MALDI)飞行时间(TOF)质谱仪中促进蛋白质和肽的电离。

Application

它被用作基质,用于改善 MALDI-TOF 上低浓度蛋白质消化物的检测。


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1B

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.


Xiangping Zhu et al.
Journal of biomolecular techniques : JBT, 14(4), 298-307 (2004-01-13)
Alpha-cyano-4-hydroxycinnamic acid (alpha-CHCA) as a matrix facilitates the ionization of proteins and peptides in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer. The matrix itself also ionizes and so do its sodium and potassium adducts. Matrix clusters and metal
Rossella Gottardo et al.
Journal of mass spectrometry : JMS, 47(1), 141-146 (2012-01-28)
Since 2004, a number of herbal blends containing different synthetic compounds mimicking the pharmacological activity of cannabinoids and displaying a high toxicological potential have appeared in the market. Their availability is mainly based on the so-called "e-commerce", being sold as
Zhiqiang Zhao et al.
Cancer letters, 342(1), 150-158 (2013-09-10)
Monocarboxylate transporter isoform 1 (MCT1) is an important member of the proton-linked MCT family and has been reported in an array of human cancer cell lines and primary human tumors. MCT1 expression is associated with developing a new therapeutic approach



全球贸易项目编号

货号GTIN
39468-10X10MG-F04061833488935
39468-10MG-KC-F04061838789945