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804185

SnAP 2-Spiro-(2-Pyr) M Reagent

Synonym(s):

tert-butyl 3-(aminomethyl)-3-((tributylstannyl)methoxy) pyrrolidine-1-carboxylate

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About This Item

Empirical Formula (Hill Notation):
C23H48N2O3Sn
Molecular Weight:
519.35
NACRES:
NA.22
PubChem Substance ID:
329768850
UNSPSC Code:
12352103
MDL number:
MFCD29049344
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description

Fp >230°F

Quality Level

100

form

powder

mp

235 °C

density

1.143 at 25 °C

functional group

amine, ether

storage temp.

−20°C

SMILES string

CCCC[Sn](CCCC)(COC1(CN(C(OC(C)(C)C)=O)CC1)CN)CCCC

InChI

1S/C11H21N2O3.3C4H9.Sn/c1-10(2,3)16-9(14)13-6-5-11(7-12,8-13)15-4;3*1-3-4-2;/h4-8,12H2,1-3H3;3*1,3-4H2,2H3;

InChI key

FITIMZOFKJTPHZ-UHFFFAOYSA-N

Application

SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode Research Group

Automate your N-heterocycle formation with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Technology spotlight: SnAP Reagents
Professor product portal: Jeffrey Bode Research Group
SnAP Reagents for the Synthesis of Piperazines and Morpholines
SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes
SnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-Heterocycles
Bespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Protocols

SnAP试剂_饱和N杂环结构单元-默克生命科学

SnAP试剂是一种种类不断扩充的试剂，现在可用来方便地合成中等环（6-9元）饱和N-杂环，包括双环和螺环结构。

SnAP Reagents

SnAP Reagents facilitate synthesis of saturated N-heterocycles for diverse structures.

Global Trade Item Number

SKUGTIN
804185-500MG04061833243688