QAMINESET
QuicTPD™ Amine Optimization Set
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About This Item
NACRES:
NA.21
Quality Level
sustainability
Greener Alternative Product
greener alternative category
storage temp.
2-8°C
General description
This set includes 4 representative partial PROTACs, each provided at 5 micromole quantity.
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Application
The QuicTPD Amine Optimization set is designed to facilitate high throughput synthesis optimization for researchers working with PROTACs.
Features and Benefits
Two of these PROTACs are tailored to target the CRBN E3 ligase, while the other two are directed towards VHL, incorporating both hydrophobic and hydrophilic linkers. By utilizing this optimization set, customers can explore a variety of reaction conditions—up to 24 or more—before proceeding to the complete screening set. This exploration includes testing different coupling reagents, solvents, and bases, allowing for a comprehensive assessment of the synthesis parameters that influence the efficiency and yield of the desired products.
Other Notes
QuicTPD Amine Screening Set
Legal Information
QuicTPD is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
target_organs
Blood
Storage Class
11 - Combustible Solids
wgk
WGK 3
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| QAMINESET-1KT | 04065272380577 |