H1009
Hydrogen peroxide solution
30 % (w/w) in H2O, contains stabilizer
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About This Item
Empirical Formula (Hill Notation):
H2O2
CAS Number:
Molecular Weight:
34.01
UNSPSC Code:
12352304
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3587191
Assay:
29.0-32.0% (titration)
Concentration:
30 % (w/w) in H2O
Form:
liquid
vapor pressure
23.3 mmHg ( 30 °C)
Quality Level
assay
29.0-32.0% (titration)
form
liquid
shelf life
~2 yr
reaction suitability
reagent type: oxidant
greener alternative product characteristics
Catalysis
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
concentration
30 % (w/w) in H2O
technique(s)
cell based assay: suitable, immunohistochemistry: suitable
density
1.110 g/cm3
suitability
suitable for DNA precipitation
application(s)
general analytical
pharmaceutical
greener alternative category
storage temp.
2-8°C
SMILES string
OO
InChI
1S/H2O2/c1-2/h1-2H
InChI key
MHAJPDPJQMAIIY-UHFFFAOYSA-N
General description
Hydrogen peroxide (H2O2), a topical antiseptic, is synthesized in aerobic cells as a byproduct of aerobic respiration. It might also be produced as an output of enzymatic reactions in peroxisomes, mitochondria, or other cell compartments.
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Application
Hydrogen peroxide solution has been used:
- to treat nasal epithelial cells for H2O2 sensitivity assays
- to treat the human immortal keratinocyte cell line (HaCaT) and the human melanoma cell line (GLL19) to induce senescence
- to incubate brain sections for bromodeoxyuridine (BrdU)/NeuN staining
- in cell proliferation assay to incubate neural stem cells (NE-4C) for in vitro experiments
Biochem/physiol Actions
Hydrogen peroxide (H2O2) is mainly used in wound cleaning. It can kill the pathogens through oxidation burst and by producing local oxygen. H2O2 functions as a signaling molecule or second messenger. It plays a key role in gene expression in numerous ways. H2O2 participates in modulating inflammation.
Features and Benefits
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Dam. 1
Storage Class
5.1B - Oxidizing hazardous materials
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
危险化学品
易制爆化学品
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Protocols
过氧化氢酶催化过氧化氢生成水和氧气。该实验方案使用分光光度法测定过氧化氢酶活性。
建立以 2,2'-连氮基-双（3-乙基苯并噻唑啉-6-磺酸）为基质的过氧化物酶测定方法。
该实验程序用于使用连苯三酚作为底物测定过氧化物酶的酶活性。
Articles
This solution is used as a substrate for detecting horseradish-peroxidase conjugates in Western blotting.
S V Lennon et al.
Cell proliferation, 24(2), 203-214 (1991-03-01)
Cell death may occur by either of two mechanisms: apoptosis or necrosis. Necrosis, the first type of cell death to be recognized, is an uncontrolled degenerative phenomenon invariably caused by noxious stimuli and is the result of irreversible failure of
Akitoshi Nakashima et al.
Scientific reports, 9(1), 11466-11466 (2019-08-09)
Pregnancy is a stress factor culminating into mild endoplasmic reticulum (ER) stress, which is necessary for placental development. However, excessive or chronic ER stress in pre-eclamptic placentas leads to placental dysfunction. The precise mechanisms through which excessive ER stress impacts
Stephen J D O'Keefe et al.
Nature communications, 6, 6342-6342 (2015-04-29)
Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (<5:100,000). The higher rates are associated with higher animal protein and fat, and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H1009-500ML | 04061833663677 |
| H1009-100ML | 04061838255938 |
| H1009-5ML | 04061833663684 |