911690
C5 Lenalidomide
≥95%
Synonym(s):
3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC® research
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About This Item
Empirical Formula (Hill Notation):
C13H13N3O3
CAS Number:
Molecular Weight:
259.26
UNSPSC Code:
12352101
NACRES:
NA.22
MDL number:
ligand
C5 Lenalidomide
Quality Level
assay
≥95%
form
powder
reaction suitability
reagent type: ligand
storage temp.
2-8°C
SMILES string
NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1
InChI
1S/C13H13N3O3/c14-8-1-2-9-7(5-8)6-16(13(9)19)10-3-4-11(17)15-12(10)18/h1-2,5,10H,3-4,6,14H2,(H,15,17,18)
InChI key
WLUIQUZGNPAKRL-UHFFFAOYSA-N
Application
C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2
target_organs
Blood
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Articles
Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 911690-100MG | 04061841399476 |
| 911690-50MG-KC | 04065272121873 |