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Merck
CN

925454

AdCyBrettPhos Pd G6 Br

powder

Synonym(s):

Adamantan-1-yl(cyclohexyl)(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphane

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About This Item

Empirical Formula (Hill Notation):
C46H61BrF3O2PPd
Molecular Weight:
920.27
UNSPSC Code:
41116105
NACRES:
NA.22
Form:
powder
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Product Name

AdCyBrettPhos Pd G6 Br,

product line

Buchwald precatalyst Generation 6

form

powder

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

SMILES string

Br[Pd](C1=CC=C(C=C1)C(F)(F)F)P(C(C(OC)=CC=C2OC)=C2C(C(C(C)C)=CC(C(C)C)=C3)=C3C(C)C)(C4CCCCC4)C56C[C@H]7C[C@H](C[C@H](C7)C6)C5

Application

AdCyBrettPhos Pd G6 Br is a G6 Buchwald precatalyst. The G6 precatalysts are air-stable, palladium-based oxidative addition complexes (OACs) that offer an alternative to the previously developed classes of palladacycle precatalysts. Unlike previous generations, the bulkiest biarylphosphine ligand precatalysts are readily prepared. These precatalysts have been shown to be effective for many reactions, including C-N, C-O, and C-F cross couplings.

Learn more about G6 Buchwald precatalysts


Storage Class

11 - Combustible Solids

wgk

WGK 3



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Articles

Buchwald G6 precatalysts are oxidative addition complexes that are thermally, air, and moisture stable. The catalyst activation doesn’t require a base and generates innocuous byproducts.





Global Trade Item Number

SKUGTIN
925454-100MG04065267495774