900601
3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride
≥95%
Synonym(s):
Formyl sulfonyl fluoride alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C12H13FO3SSi
CAS Number:
Molecular Weight:
284.38
UNSPSC Code:
12352200
NACRES:
NA.22
Assay:
≥95%
Form:
solid
assay
≥95%
form
solid
reaction suitability
reaction type: click chemistry
storage temp.
−20°C
SMILES string
O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1
Application
3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Articles
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 900601-100MG | 04061833250440 |