900860
3-Amino-5-ethynylbenzenesulfonyl fluoride
≥95%
Synonym(s):
Amino sulfonyl fluoride alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C8H6FNO2S
CAS Number:
Molecular Weight:
199.20
UNSPSC Code:
12352200
NACRES:
NA.22
Assay:
≥95%
Form:
powder or crystals
assay
≥95%
form
powder or crystals
storage temp.
−20°C
SMILES string
NC1=CC(S(=O)(F)=O)=CC(C#C)=C1
Application
3-Amino-5-ethynylbenzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 900860-50MG | 04061833251263 |